"The Day a friend shall not avail a friend"—a guardian shall not avail a ward—"at all," meaning he shall not bear any of their sins. "Nor shall they be helped," meaning they shall not be protected from the punishment.
﴿يَوْمَ لَا يُغْنِي مَوْلًى عَنْ مولى﴾ ولي عَن ولي ﴿شَيْئا﴾ أَي: لَا يحمل من ذنوبهم شَيْئا ﴿وَلَا هم ينْصرُونَ﴾ يمْنَعُونَ من الْعَذَاب