[By thy life] is an oath. [They are indeed in their intoxication] means: in their misguidance. [Wandering blindly] means: they are confused.

Muhammad said: The words al-'umr and al-'amr, according to the linguistic scholars, carry the same meaning. When it is used in an oath, the first letter is vocalized with a fatha (vowel sign 'a') due to its frequent usage, because the fatha is lighter [to pronounce].